Facile Synthesis of Manganese Tellurite Nanoparticles for Magnetic Resonance Imaging-Guided Photothermal Therapy

In this study, manganese tellurite (MnTeO₃) nanoparticles are developed as theranostic agents for magnetic resonance imaging (MRI)-guided photothermal therapy of tumor. MnTeO₃ nanoparticles are synthesized via a simple one-step method. The as-synthesized MnTeO₃ nanoparticles with uniform size show good biocompatibility. In particular, MnTeO₃ nanoparticles exhibit a high photothermal conversion efficiency (η = 26.3%), which is higher than that of gold nanorods. Moreover, MnTeO₃ nanoparticles also have high MRI performance. The longitudinal relaxivity (r₁) value of MnTeO₃ nanoparticles is determined to be 8.08 ± 0.2 mm ⁻¹ s⁻¹, which is higher than that of clinically approved T₁-contrast agents Gd-DTPA (4.49 ± 0.1 mm ⁻¹ s⁻¹). The subsequent MnTeO₃ nanoparticles-mediated photothermal therapy displays a highly efficient ablation of tumor cells both in vitro and in vivo with negligible toxicity. It is demonstrated that MnTeO₃ nanoparticles can serve as promising theranostic agents with great potentials for MRI-guided photothermal therapy.     

Equation for Condensed Matter Phase Transitions

Russian Physics Journal - A unified equation for the pressure drop in the apparatus with the stationary and fluidized granular layers is derived. The resulting recurrent equation is used to...     

On the $$\bar\partial$$ -problem and dressing method for the complex vector modified KdV equation

Theoretical and Mathematical Physics - Starting from a $$5\times 5$$ local matrix $$\bar\partial$$ -problem, we successfully use the $$\bar\partial$$ -dressing method to derive a hierarchy of...     

Formation of High-Order Structures in Solution by CBS-Pyrophosphatase from D. hafniense

Crystallography Reports - To solve the question about the oligomeric state of wild-type CBS-pyrophosphatase (CBS-PPase) from D. hafniense, this enzyme has been studied using two independent...     

On a Method for Solving Boundary Value Problems of Aerohydrodynamics

Journal of Applied and Industrial Mathematics - Under consideration is the well-known boundary value problem of aerohydrodynamics in which it is required to find the velocity distribution of fluid...     

Evolutionary Development and Structural Diversity of Natural Antimicrobial Peptides,Peptidometics, and Cationic Amphiphiles Based on Amino Acids

Russian Journal of General Chemistry - The review article traces the main trends of the synthetic approach to the solution of the problem of overcoming the resistance of pathogenic bacterial...     

Critical assessment of thermodynamic properties of perovskite-type cesium lead chloride CsPbCl3

Journal of Thermal Analysis and Calorimetry - The results of thermochemical study of the CsPbCl3 formation thermodynamics available in literature were critically evaluated by comparison with those...     

Heterostructured MoS2/GPC anode: the synergistic lithium storage performance and lithiation kinetics

Journal of Solid State Electrochemistry - Grapefruit peel carbon (GPC) is prepared from waste grapefruit peel and further used as substrate for in situ construction of MoS2 arrays, forming MoS2/GPC...     

Building 2D classification models and 3D CoMSIA models on small-molecule inhibitors of both wild-type and T790M/L858R double-mutant EGFR

Molecular Diversity - Epidermal growth factor receptor (EGFR) has received widespread attention because it is an important target for anticancer drug design. Mutations in the EGFR, especially the...